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Abstract Number: 5086
Do positive psychological traits predict treatment response in patients with Major Depressive and/or Generalized Anxiety Disorders?

Do positive psychological traits predict treatment response in patients with Major Depressive and/or Generalized Anxiety Disorders?
Poster
Yes
Psychosocial and Biomedical Research
Yasin Ibrahim MD
Yasin.Ibrahim@ttuhsc.edu

Objectives: This study aims to examine four positive psychology traits (resilience, loneliness, religiousness, and engaged living) as predictors of treatment response in patients with depression and/or anxiety.



Methods: This is a prospective study aims to include 200 patients with new diagnosis of depressive and/or anxiety disorders. Positive psychology traits (resilience, loneliness, religiousness, and engaged living) will be determined by Connor-Davidson Resilience Scale (CD-RISC 10 item scale), De Jong Gierveld 6 item scale, Duke University Religious index scale, and Engaged Living Scale, respectively. These measures will be administered during orientation prior to first evaluation, on week 12 to monitor any score changes.



The severity of depression and anxiety will be measured during the first visit evaluationand at weeks 8 and 12 to monitor for response and at 12 and 24 months to monitor for relapse. Severity symptoms will be measured by Patient Health Questionnaire 9 item (PHQ-9) for depressive symptoms and Generalized Anxiety Disorder 7 item (GAD-7) for anxiety.



Improvement and relapse rates between patients with high scores on the positive psychology scales will be compared to those who had lower scores. The post treatment score changes in resilience, loneliness, engaged living, and spirituality/religiosity scales will be monitored as well.



Results/Discussion: Researchers hypothesize that higher pretreatment scores of resilience, engaged living, and spirituality and lower pretreatment scores of loneliness are associated with better treatment response and lower relapse rates in patients diagnosed with depressive and/or anxiety disorders. They also hypothesize that antidepressants can increase resilience, engaged living, and spirituality/religiosity while decreasing loneliness. Results of this project can inform if resilience, loneliness, engaged living and/or spirituality/religiosity could be utilized to help predict response to antidepressants and/or anxiolytics. Such knowledge could have clinical implications.

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Depressive Disorders
Anxiety Disorders

Submitter Only


Nimra  
 
Pasha  
nimrapasha@gmail.com  

POSTER PRESENTER
Nimra  
 
Pasha  
nimrapasha@gmail.com  

CO-AUTHOR
Samuel  
 
Yang  
samuel.yang@ttuhsc.edu  

CO-AUTHOR
Ashish  
K  
Sarangi  
MD  
ashish.sarangi@ttuhsc.edu  

CO-AUTHOR
Regina  
 
Baronia  
MD  
regina.baronia@ttuhsc.edu  

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